Development of a Microfluidic Device for Performing Sample Preconcentration and Capillary Electrophoresis Separation

نویسندگان

  • Honggu Chun
  • J. P. Alarie
  • J. M. Ramsey
چکیده

We report on a microfabricated device for sample preconcentration and capillary electrophoresis (CE) separation in a glass microchip. The device allows highly efficient anion-selective preconcentration to be performed with a micro-nanomicrochannel structure. An integrated cross channel enables gate-injection of the preconcentrated sample into the analysis channel for CE separation. Sample preconcentration and corresponding enhanced CE separation signal have been demonstrated with TRITC-tagged peptides.

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تاریخ انتشار 2010